Quinfamide

Identification
Name
 　

 
Quinfamide
Synonyms
 　

 
1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline
Chinese Names
 　

 
喹法米特; 1-(二氯乙酰基)-6-(2-呋喃甲酰氧基)-1,2,3,4-四氢喹啉
Molecular Structure
 　

 
Quinfamide, 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline CAS #: 62265-68-3
　

 
Molecular Formula
 　

 
C16H13Cl2NO4
Molecular Weight
 　

 
354.18
CAS Registry Number
 　

 
62265-68-3
EINECS
 　

 
263-478-1
Properties
Crystals from ethyl acetate, mp 150.5-151°
Development Status: Launched 1984.
Melting Point: Mp 150.5-151 deg
Partition Coefficient: Log P 3.6 (calc).
Use
Antiamoebic drug.
Synonym
2-furoic acid ester with 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinol; 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline Manufacturers’
喹法米特
1-(二氯乙酰基)-1,2,3,4-四氢-6-喹啉基-2-呋喃羧酸酯
Amenide
Amenox
Quinfamide
Win 40014
Quinfamide,INN,USAN
1-(Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl 2-furancarboxylate,9CI
Win 40014
Reference
Bailey, D.M. et al.,J. Med. Chem.,1979, 22, 599 (synth, pharmacol) Baker, J.F. et al.,Arch. Int. Pharmacodyn. Ther.,1982, 258, 29 (metab) Martindale, The Extra Pharmacopoeia,30th edn., Pharmaceutical Press, London, 1993, 525 [00046149-2]

　

 

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