Orciprenaline

Identification
Name
 　

 
Orciprenaline
Synonyms
 　

 
5-(1-Hydroxy-2-propan-2-ylamino-ethyl)benzene-1,3-diol; 5-[1-Hydroxy-2-(1-methylethylamino)ethyl]benzene-1,3-diol
Chinese Names
 　

 
奥西那林; 5-(1-羟基-2-异丙基氨基乙基)苯-1,3-二酚
Molecular Structure
 　

 
Orciprenaline, 5-(1-Hydroxy-2-propan-2-ylamino-ethyl)benzene-1,3-diol, 5-[1-Hydroxy-2-(1-methylethylamino)ethyl]benzene-1,3-diol CAS #: 586-06-1
　

 
Molecular Formula
 　

 
C11H17NO3
Molecular Weight
 　

 
211.26
CAS Registry Number
 　

 
586-06-1
EINECS
 　

 
209-569-1
Properties
Crystals, mp 100°
Hazard Toxicity: Human reprod. effects. LD50 (rat, orl) 3370 mg/kg.
Partition Coefficient: Log P 0.08 (calc).
Use
.beta.-Adrenoceptor agonist. Bronchodilator.
Synonym
3,5-dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol; 1-(3,5-dihydroxyphenyl)-2-isopropylaminoethanol; 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-isopropylaminoethane; orciprenaline
Alotec
Alupent
Astmopent
Astop
Dosalupent
Ipradol "Isis-Portugal"
Lenasma
Metaprel
metaproterenol sulfate
Novasmasol
Orciprenaline sulfate
Sedasma
Th 152
Orciprenaline,BAN,INN
5-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,3-benzenediol,9CI
3,5-Dihydroxy-α-[(isopropylamino)methyl]benzyl alcohol,8CI
1-(3,5-Dihydroxyphenyl)-2-(isopropylamino)ethanol
Metaproterenol
Reference
Belg. Pat.,1962, 611 502; CA,57, 13678 (synth, resoln, pharmacol) Brittain, R.T. et al.,Adv. Drug Res.,1970, 5, 197 (rev) Dengler, H.J., Arch. Int. Pharmacodyn. Ther.,1974, 223, 71 (metab) Kracmar, J. et al.,Pharmazie,1976, 31, 614 (uv) Martindale, The Extra Pharmacopoeia,30th edn., Pharmaceutical Press, London, 1993, 1250 Lewis, R.J., Sax’s Dangerous Properties of Industrial Materials,8th edn., Van Nostrand Reinhold, 1992, DMV800 [00052419-9]

　

 

　

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