Levosimendan

Identification
Name
 　

 
Levosimendan
Synonyms
 　

 
Mesoxalonitrile (-)-{p-[(R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl}hydrazone
Chinese Names
 　

 
左西孟旦; 左旋西孟旦
Molecular Structure
 　

 
Levosimendan, Mesoxalonitrile (-)-{p-[(R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl}hydrazone CAS #: 141505-33-1
　

 
Molecular Formula
 　

 
C14H12N6O
Molecular Weight
 　

 
280.29
CAS Registry Number
 　

 
141505-33-1
Properties
Yellow crystalline powder, mp 210-214° [alpha]D25 -566°(tetrahydrofurane/methanol). Soluble in water. pKa 6.3. LD50 in male, female mice, male rats (mg/kg): 156, 152, 103 orally; 32, 50, 57 i.v. (Pagel).
Synonym
(-)-[p[(R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazone mesoxalonitrile; (R)-simendan Manufacturers’

　

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