Daunorubicin
Identification
Name
Daunorubicin
Synonyms
Daunomycin, (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
Chinese Names
柔红霉素;正定霉素;柔毛霉素;红比霉素;红卫霉素;红保霉素
Molecular Structure
Molecular Formula
C27H29NO10
Molecular Weight
527.52
CAS Registry Number
20830-81-3
EINECS
244-069-7
Properties
mp 208-209° LD50 in mice, rats (mg/kg): 20, 13 i.v.; 5, 8 i.p. (DiMarco, 1977).
Storage Temperature:Store at 2-8.degree.C
Hazard Toxicity: Possible human carcinogen. LD50 (mus, orl) 205 mg/kg. LD50 (rat, orl) 336 mg/kg. Exp. carcinogen. Exp. reprod. and teratogenic effects.
General Statement: Anthracycline antibiotic.
Synthesis: Isol. from Streptomyces peucetius.
Physics Description: Red [...]